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Multi-omics analysis of hepatopancreas of red seabream (Pagrus major) fed a soybean meal-based diet
https://fra.repo.nii.ac.jp/records/2000134
https://fra.repo.nii.ac.jp/records/2000134aa7d5f6f-3fb1-49a9-858b-98bcab0f29e5
| 名前 / ファイル | ライセンス | アクション |
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23334000_post-print.pdf (3.2 MB)
Download is available from 2025/9/15.
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
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| 公開日 | 2024-02-08 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Multi-omics analysis of hepatopancreas of red seabream (Pagrus major) fed a soybean meal-based diet | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Red seabrea; Soybean meal; Transcriptome; Metabolome; Hepatopancreas | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| 著者 |
吉永, 葉月
× 吉永, 葉月× 安池, 元重× 馬久地, みゆき× 相馬, 智史× 山本, 剛史× 村下, 幸司
WEKO
293
× 松成, 宏之× 奥, 宏海 |
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Dietary intake of a large amount of soybean meal (SBM) adversely affects the physiological condition and growth of fish, while SBM is a commonly used substitute for fish meal (FM) in aquaculture feed. In the present study, we investigated the effects of feeding an SBM-based diet (SBMD) for 8 weeks on hepatopancreatic metabolic condition in red seabream Pagrus major, using comprehensive analyses of the transcriptome and metabolome. Compared with fish fed an FM-based control diet (FMD), fish fed the SBMD showed delayed growth, decreases in hepatopancreatic somatic index and serum cholesterol concentration, and hepatopancreatic tissue degeneration. Transcriptome sequencing analysis identified 454, 353, and 566 differentially expressed genes at 2, 4, and 8 weeks, respectively. Analysis of the hepatopancreas metabolome using capillary electrophoresis-time-of-flight mass spectrometry identified 301 quantifiable metabolites in the FMD and SBMD groups. Transcriptome analysis showed increases in gene expression levels in the terpenoid and steroid biosynthesis pathways, suggesting that hepatic cholesterol biosynthesis was up-regulated in the SBMD group. In addition, the results of transcriptome and metabolome analyses suggested that the SBMD affects glutathione and glycine metabolism. These findings provide valuable information that enhances our understanding of the effects of dietary SBM intake on red seabream metabolism. | |||||||||||
| 言語 | en | |||||||||||
| 書誌情報 |
en : Aquaculture 巻 574, p. 739631, 発行日 2023-09-15 |
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| 出版者 | ||||||||||||
| 出版者 | Elsevier | |||||||||||
| 言語 | en | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 0044-8486 | |||||||||||
| DOI | ||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | 10.1016/j.aquaculture.2023.739631 | |||||||||||
| 情報源 | ||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||
| 識別子タイプ | Local | |||||||||||
| 関連識別子 | 23334000 | |||||||||||
| 言語 | ja | |||||||||||
| 関連名称 | 水産技術研究所 養殖部門 生理機能部 | |||||||||||
| 関連サイト | ||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||
| 識別子タイプ | URI | |||||||||||
| 関連識別子 | https://www.sciencedirect.com/science/article/pii/S0044848623004052 | |||||||||||
| 言語 | en | |||||||||||
| 関連名称 | Aquaculture | |||||||||||
| 著者版フラグ | ||||||||||||
| 出版タイプ | AO | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_b1a7d7d4d402bcce | |||||||||||
