{"created":"2024-07-16T03:03:46.186868+00:00","id":2009863,"links":{},"metadata":{"_buckets":{"deposit":"202f37de-f2cb-4a6b-9334-a479381f80e1"},"_deposit":{"created_by":10,"id":"2009863","owner":"92","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"2009863"},"status":"published"},"_oai":{"id":"oai:fra.repo.nii.ac.jp:02009863","sets":["15"]},"author_link":["293"],"control_number":"2009863","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2024-03-02","bibliographicIssueDateType":"Issued"},"bibliographicNumberOfPages":"15","bibliographicPageEnd":"423","bibliographicPageStart":"409","bibliographicVolumeNumber":"90","bibliographic_titles":[{"bibliographic_title":"Fisheries Science","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Agouti-related protein (Agrp) is an orexigenic peptide hormone found in fish and other vertebrates. Understanding appetite regulation is important for improving production performance in aquaculture systems. However, information on appetite-related hormones in yellowtail is still fragmentary. In this study, two distinct agrpgenes (i.e., agrp1 and agrp2) were cloned from the yellowtail brain. Brain distribution and response of the agrp genes to fasting, along with other candidate orexigenic peptide hormone-related genes including neuropeptide Y (npy) and melanin-concentrating hormones (mch1 and mch2), were studied. The highest expression level of those genes was observed in the hypothalamus, except for npy. After fasting, agrp1 and npy increased significantly in the hypothalamus, whereas agrp2 in the olfactory bulb and cerebellum decreased significantly. After feeding with a fishmeal (FM)-based diet and addition of a fishmeal soluble fraction (FMS), hypothalamic agrp1, agrp2, mch1, and mch2 increased, whereas hypothalamic npy decreased significantly. From the fasting experiment, agrp1 and npy may function as orexigenic hormones in yellowtail; however, the function of other hormones warrants further research. Expression of all the analyzed appetite-related hormonal genes might respond to the smell/taste of fishmeal through sensory organs. Furthermore, npy and agrp1 may enhance appetite through different mechanisms in yellowtail.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer","subitem_publisher_language":"en"}]},"item_10001_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"水産技術研究所 養殖部門 生理機能部"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"23334037","subitem_relation_type_select":"Local"}}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"en","subitem_relation_name_text":"SPRINGER LINK"}],"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://link.springer.com/article/10.1007/s12562-024-01759-0","subitem_relation_type_select":"URI"}}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"1444-2906","subitem_source_identifier_type":"EISSN"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0919-9268","subitem_source_identifier_type":"PISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Kochi University","affiliationNameLang":"en"},{"affiliationName":"高知大学","affiliationNameLang":"ja"},{"affiliationName":"コウチダイガク","affiliationNameLang":"ja-Kana"}]}],"creatorNames":[{"creatorName":"Fukuda, Haruhisa","creatorNameLang":"en","creatorNameType":"Personal"},{"creatorName":"フクダ, ハルヒサ","creatorNameLang":"ja","creatorNameType":"Personal"},{"creatorName":"フクダ, ハルヒサ","creatorNameLang":"ja-Kana","creatorNameType":"Personal"}]},{"creatorNames":[{"creatorName":"Murashita, Koji","creatorNameLang":"en","creatorNameType":"Organizational"},{"creatorName":"村下, 幸司","creatorNameLang":"ja","creatorNameType":"Organizational"},{"creatorName":"ムラシタ, コウジ","creatorNameLang":"ja-Kana","creatorNameType":"Organizational"}],"familyNames":[{"familyName":"Murashita","familyNameLang":"en"},{"familyName":"村下","familyNameLang":"ja"},{"familyName":"ムラシタ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Koji","givenNameLang":"en"},{"givenName":"幸司","givenNameLang":"ja"},{"givenName":"コウジ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"293","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60597649","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=60597649"},{"nameIdentifier":"0000-0003-4032-1426","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0003-4032-1426"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Ehime University","affiliationNameLang":"en"},{"affiliationName":"愛媛大学","affiliationNameLang":"ja"},{"affiliationName":"エヒメダイガク","affiliationNameLang":"ja-Kana"}]}],"creatorNames":[{"creatorName":"Senzui, Ayaka","creatorNameLang":"en","creatorNameType":"Personal"},{"creatorName":"センズイ, アヤカ","creatorNameLang":"ja","creatorNameType":"Personal"},{"creatorName":"センズイ, アヤカ","creatorNameLang":"ja-Kana","creatorNameType":"Personal"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-06-13"}],"filename":"Fukada et al.  Candidate orexigenic peptide hormone-related genes.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://fra.repo.nii.ac.jp/record/2009863/files/Fukada et al.  Candidate orexigenic peptide hormone-related genes.pdf"},"version_id":"e96b6887-deeb-4fea-ad71-8e48a9800bab"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Agouti-related protein; Appetite-related hormone; Neuropeptide Y; Melanin-concentrating hormone; Yellowtail","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Candidate orexigenic peptide hormone-related genes in yellowtail Seriola quinqueradiata: cloning and tissue distribution of two distinct agouti-related protein genes and response of five candidate appetite-related genes to fasting, fishmeal soluble fraction addition, and a fishmeal-based diet","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Candidate orexigenic peptide hormone-related genes in yellowtail Seriola quinqueradiata: cloning and tissue distribution of two distinct agouti-related protein genes and response of five candidate appetite-related genes to fasting, fishmeal soluble fraction addition, and a fishmeal-based diet","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"10","path":["15"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-07-16"},"publish_date":"2024-07-16","publish_status":"0","recid":"2009863","relation_version_is_last":true,"title":["Candidate orexigenic peptide hormone-related genes in yellowtail Seriola quinqueradiata: cloning and tissue distribution of two distinct agouti-related protein genes and response of five candidate appetite-related genes to fasting, fishmeal soluble fraction addition, and a fishmeal-based diet"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2025-09-24T07:56:42.347515+00:00"}