{"created":"2024-10-03T01:22:32.198183+00:00","id":2010872,"links":{},"metadata":{"_buckets":{"deposit":"8304dba5-5435-4209-b320-e5893ba9f19e"},"_deposit":{"created_by":10,"id":"2010872","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"2010872"},"status":"published"},"_oai":{"id":"oai:fra.repo.nii.ac.jp:02010872","sets":["1:8:1724310835301"]},"author_link":["2794","702","490"],"item_10002_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"魚類ビタミンAの胚発生での役割解明に向けて","subitem_alternative_title_language":"ja"}]},"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-12","bibliographicIssueDateType":"Issued"},"bibliographicNumberOfPages":"6","bibliographicPageEnd":"46","bibliographicPageStart":"41","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"水産総合研究センター研究報告","bibliographic_titleLang":"ja"},{"bibliographic_title":"Bulletin of  Fisheries Research Agency","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Embryonic development of organs and tissues in viviparous organisms such as mammals, particularly organs such as the central nervous system, heart and skeletons, is dependent upon vitamin A supplemented from the mother. Conversely, in fish, which are oviparous, embryogenesis is entirely dependent on nutrients stored mainly as yolk within eggs during vitellogenesis. It is therefore possible that abnormalities in seed production by broodstock may arise during embryogenesis in an aquacultural setting due to vitamin A deficiency or hypervitaminosis. The authors hypothesize that, not only is vitamin A metabolism essential to the development of mature female fish, but vitamin A transfer to the eggs is essential for healthy seed production. Here we review the role of vitamin A in mammals and fish. In addition, we describe the molecular characteristics and gene expression patterns in Takifugu rubripes retinaldehyde dehydrogenase 2 (raldh2), which converts retinal to retinoic acid, an active form of vitamin A that controls the mRNA expression of various genes involved in embryogenesis.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"水産総合研究センター","subitem_publisher_language":"ja"}]},"item_10002_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"fra_k_26_41","subitem_relation_type_select":"Local"}}]},"item_10002_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"日本農学文献記事索引（AgriKnowledge）"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://agriknowledge.affrc.go.jp/RN/2010770090","subitem_relation_type_select":"URI"}}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11589591","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-9894","subitem_source_identifier_type":"PISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Uji, Susumu","creatorNameLang":"en"},{"creatorName":"宇治, 督","creatorNameLang":"ja"},{"creatorName":"ウジ, ススム","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Uji","familyNameLang":"en"},{"familyName":"宇治","familyNameLang":"ja"},{"familyName":"ウジ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Susumu","givenNameLang":"en"},{"givenName":"督","givenNameLang":"ja"},{"givenName":"ススム","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"702","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40372049","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40372049"}]},{"creatorNames":[{"creatorName":"Kurokawa, Tadahide","creatorNameLang":"en","creatorNameType":"Personal"},{"creatorName":"黒川, 忠英","creatorNameLang":"ja","creatorNameType":"Personal"},{"creatorName":"クロカワ, タダヒデ","creatorNameLang":"ja-Kana","creatorNameType":"Personal"}],"familyNames":[{"familyName":"Kurokawa","familyNameLang":"en"},{"familyName":"黒川","familyNameLang":"ja"},{"familyName":"クロカワ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Tadahide","givenNameLang":"en"},{"givenName":"忠英","givenNameLang":"ja"},{"givenName":"タダヒデ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"490","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50372032","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=50372032"}]},{"creatorNames":[{"creatorName":"Suzuki, Toru","creatorNameLang":"en","creatorNameType":"Personal"},{"creatorName":"鈴木, 徹","creatorNameLang":"ja","creatorNameType":"Personal"},{"creatorName":"スズキ, トオル","creatorNameLang":"ja-Kana","creatorNameType":"Personal"}],"familyNames":[{"familyName":"Suzuki","familyNameLang":"en"},{"familyName":"鈴木","familyNameLang":"ja"},{"familyName":"スズキ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Toru","givenNameLang":"en"},{"givenName":"徹","givenNameLang":"ja"},{"givenName":"トオル","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2794","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-02"}],"filename":"fra_k_26_41.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"url":"https://fra.repo.nii.ac.jp/record/2010872/files/fra_k_26_41.pdf"},"version_id":"1b803f79-c25e-4f62-a8d0-d7d4d4b1f40e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"vitamin A; early development; malformation; metabolic pathway of vitamin A; raldh2","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"トラフグraldh2のクローニング","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"トラフグraldh2のクローニング","subitem_title_language":"ja"},{"subitem_title":"Molecular cloning of raldh2 from Takifugu rubripes","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"10","path":["1724310835301"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-02"},"publish_date":"2024-10-02","publish_status":"0","recid":"2010872","relation_version_is_last":true,"title":["トラフグraldh2のクローニング"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2025-03-27T07:39:16.835859+00:00"}