{"created":"2024-10-03T01:22:51.598446+00:00","id":2010876,"links":{},"metadata":{"_buckets":{"deposit":"38a85952-a621-4800-b47d-7d9efd74d029"},"_deposit":{"created_by":10,"id":"2010876","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"2010876"},"status":"published"},"_oai":{"id":"oai:fra.repo.nii.ac.jp:02010876","sets":["1:8:1724310835301"]},"author_link":["1831"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-12","bibliographicIssueDateType":"Issued"},"bibliographicNumberOfPages":"6","bibliographicPageEnd":"82","bibliographicPageStart":"77","bibliographicVolumeNumber":"26","bibliographic_titles":[{"bibliographic_title":"水産総合研究センター研究報告","bibliographic_titleLang":"ja"},{"bibliographic_title":"Bulletin of  Fisheries Research Agency","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Peptides structurally related to vertebrate insulin have been identified in invertebrates including mollusks. In the pond snail, Lymnaea stagnalis , clusters of neurons called light green cells in the cerebral ganglia produce and release molluscan insulin-related peptides (MIPs) which are suggested to stimulate the use of hemolymph glucose as an energy source by growing tissues. In the sea hare, Aplysia californica , Aplysia insulin (AI) is produced in the central region of the cerebral ganglia. The expression of AI mRNA decreases when the animal is deprived of food, and injections of AI reduce hemolymph glucose levels. These results suggest that the gastropod insulin-related peptides play important roles in growth control and carbohydrate homeostasis. In bivalves, the structure and gene expression of the insulin-related peptide are detailed only in the Pacific oyster, Crassostrea gigas . The expression of the oyster insulin-related peptide (oIRP) mRNA increases in March prior to growth and germ cell development, and decreases in July after active spawning. To gain insight into the physiological function of oIRP, changes in the oIRP mRNA levels under food deprivation or glucose administration were examined, but significant changes in the gene expression were not detected.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"水産総合研究センター","subitem_publisher_language":"ja"}]},"item_10002_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"fra_k_26_77","subitem_relation_type_select":"Local"}}]},"item_10002_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"日本農学文献記事索引（AgriKnowledge）"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://agriknowledge.affrc.go.jp/RN/2010770095","subitem_relation_type_select":"URI"}}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11589591","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-9894","subitem_source_identifier_type":"PISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Awaji, Masahiko","creatorNameLang":"en"},{"creatorName":"淡路, 雅彦","creatorNameLang":"ja"},{"creatorName":"アワジ, マサヒコ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Awaji","familyNameLang":"en"},{"familyName":"淡路","familyNameLang":"ja"},{"familyName":"アワジ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Masahiko","givenNameLang":"en"},{"givenName":"雅彦","givenNameLang":"ja"},{"givenName":"マサヒコ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"1831","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20371825","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=20371825"}]},{"creatorNames":[{"creatorName":"Moriyama, Shunsuke","creatorNameLang":"en","creatorNameType":"Personal"},{"creatorName":"森山, 俊介","creatorNameLang":"ja","creatorNameType":"Personal"},{"creatorName":"モリヤマ, シュンスケ","creatorNameLang":"ja-Kana","creatorNameType":"Personal"}],"familyNames":[{"familyName":"Moriyama","familyNameLang":"en"},{"familyName":"森山","familyNameLang":"ja"},{"familyName":"モリヤマ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Shunsuke","givenNameLang":"en"},{"givenName":"俊介","givenNameLang":"ja"},{"givenName":"シュンスケ","givenNameLang":"ja-Kana"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-02"}],"filename":"fra_k_26_77.pdf","filesize":[{"value":"422.4 KB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"url":"https://fra.repo.nii.ac.jp/record/2010876/files/fra_k_26_77.pdf"},"version_id":"e59fd5aa-6965-4a5e-ba3d-8359e36d0ab7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"insulin; Lymnaea; Aplysia; Crassostrea ; Mollusca","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"貝類インスリン関連ペプチドの生理機能","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"貝類インスリン関連ペプチドの生理機能","subitem_title_language":"ja"},{"subitem_title":"Physiological function of the insulin-related peptides in molluscs.","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"10","path":["1724310835301"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-02"},"publish_date":"2024-10-02","publish_status":"0","recid":"2010876","relation_version_is_last":true,"title":["貝類インスリン関連ペプチドの生理機能"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2025-03-31T07:29:06.551106+00:00"}