{"created":"2024-10-15T05:29:58.601059+00:00","id":2012106,"links":{},"metadata":{"_buckets":{"deposit":"96da82d4-5d79-41a5-a43d-aee6dff89d98"},"_deposit":{"created_by":10,"id":"2012106","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"2012106"},"status":"published"},"_oai":{"id":"oai:fra.repo.nii.ac.jp:02012106","sets":["1:6:1724312738723"]},"author_link":["1242","1243","1240"],"control_number":"2012106","item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicNumberOfPages":"6","bibliographicPageEnd":"250","bibliographicPageStart":"245","bibliographicVolumeNumber":"65","bibliographic_titles":[{"bibliographic_title":"水産大学校研究報告","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of National Fisheries University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The anti-inflammatory effects of phlorotannins identified in the hydrophilic fraction of the brown alga, Eisenia arborea, were previously determined in vivo and in vitro. Here, we investigated the in vivo effect of the lipophilic fraction from this alga in mice. In ICR mice, ear swelling was induced by three sensitizers: arachidonic acid (AA), 12-O-tetradecanoylphorbol-13-acetate (TPA) and oxazolone (OXA). Swelling induced by AA or TPA was suppressed in a dose dependent manner after the said lipophilic fraction was applied to the mouse ears at a dose of 0.01, 0.1 and 1 mg/mouse, respectively. The suppression was similar to that by epigallocatechin gallate (EGCG), a typical natural inhibitor. On the other hand, the suppressive effect of the fraction at 1 mg/mouse on ear swelling induced by OXA was significantly lower than that of EGCG (ρ < 0.01). At a dose of 0.01 and 0.1 mg/mouse, no suppression by the fraction was observed. Therefore, lipophilic active components in the fraction may suppress immediate inflammatory reactions induced by AA or TP A, but not show suppressive effects on the delayed-type (type IV allergy) inflammatory reactions induced by OXA.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"水産大学校","subitem_publisher_language":"ja"},{"subitem_publisher":"National Fisheries University","subitem_publisher_language":"en"}]},"item_10002_relation_16":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"fishu_k_65_245","subitem_relation_type_select":"Local"}}]},"item_10002_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"en","subitem_relation_name_text":"agriknowledge"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://agriknowledge.affrc.go.jp/RN/2010922174","subitem_relation_type_select":"URI"}}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00124678","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0370-9361","subitem_source_identifier_type":"PISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Sugiura, Yoshimasa","creatorNameLang":"en"},{"creatorName":"杉浦, 義正","creatorNameLang":"ja"},{"creatorName":"スギウラ, ヨシマサ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Sugiura","familyNameLang":"en"},{"familyName":"杉浦","familyNameLang":"ja"},{"familyName":"スギウラ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Yoshimasa","givenNameLang":"en"},{"givenName":"義正","givenNameLang":"ja"},{"givenName":"ヨシマサ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"1243","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60608107","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=60608107"},{"nameIdentifier":"0000-0001-6525-3066","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0001-6525-3066"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Usui, Masakatsu","creatorNameLang":"en"},{"creatorName":"臼井, 将勝","creatorNameLang":"ja"},{"creatorName":"ウスイ, マサカツ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Usui","familyNameLang":"en"},{"familyName":"臼井","familyNameLang":"ja"},{"familyName":"ウスイ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Masakatsu","givenNameLang":"en"},{"givenName":"将勝","givenNameLang":"ja"},{"givenName":"マサカツ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"1242","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50399656","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=50399656"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Miyata, Masaaki","creatorNameLang":"en"},{"creatorName":"宮田, 昌明","creatorNameLang":"ja"},{"creatorName":"ミヤタ, マサアキ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Miyata","familyNameLang":"en"},{"familyName":"宮田","familyNameLang":"ja"},{"familyName":"ミヤタ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Masaaki","givenNameLang":"en"},{"givenName":"昌明","givenNameLang":"ja"},{"givenName":"マサアキ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"1240","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90239418","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90239418"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-11"}],"filename":"fishu_k_65_245.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"url":"https://fra.repo.nii.ac.jp/record/2012106/files/fishu_k_65_245.pdf"},"version_id":"27378e35-218f-4715-a80e-0a1282b4ccb0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Eisenia arborea; anti-inflammation; allergic reactions; lipophilic fraction","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"マウス耳介浮腫に対する褐藻サガラメ由来の脂溶性成分による抑制効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"マウス耳介浮腫に対する褐藻サガラメ由来の脂溶性成分による抑制効果","subitem_title_language":"ja"},{"subitem_title":"The suppressive effect of the lipophilic fraction of Eisenia arborea on ear swelling in mice","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"10","path":["1724312738723"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-11"},"publish_date":"2024-10-11","publish_status":"0","recid":"2012106","relation_version_is_last":true,"title":["マウス耳介浮腫に対する褐藻サガラメ由来の脂溶性成分による抑制効果"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2025-05-07T01:59:29.454369+00:00"}