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ラットの血液凝固系および血小板凝集に対するイワシ油および綿実油の繰り返し経口投与の効果
https://fra.repo.nii.ac.jp/records/2011816
https://fra.repo.nii.ac.jp/records/2011816c30855b6-b621-4501-b120-bbc5a2b53dce
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2024-10-11 | |||||
タイトル | ||||||
タイトル | ラットの血液凝固系および血小板凝集に対するイワシ油および綿実油の繰り返し経口投与の効果 | |||||
言語 | ja | |||||
タイトル | ||||||
タイトル | Effects of repeated oral administration lf sardine oil and cotton seed oil on blood coagulation and platelet aggregation in rats | |||||
言語 | en | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | arachidonic acid; blood cells; collagen; fish oils; haematology | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
松下, 映夫
× 松下, 映夫× 井上, 晋一× 田中, 竜介 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Effects of repeated oral administration of sardine oil and cotton seed oil on blood coagulation and platelet aggregation in rats were examined. Treatments of rats with 3.0g/kg/day of sardine oil and cotton seed oil for 28 days changed in the fatty acid composition of lipids in their liver and blood. The levels of n- 3 and n- 6 unsaturated fatty acids showed the tendency to increase and decrease in the rats treated with sardine oil (sardine oil group) in comparison with control rats. Meanwhile, the change in fatty acid composition into the opposite direction was observed in the case of rats treated with cotton seed oil (cotton seed oil group). Treatments of rats with sardine oil and cotton seed oil changed in the parameters of thromboelastogram reflecting that whole blood coagulation system was slightly inhibited and enhanced, respectively. These results support that feeding of fish oil including n- 3 unsaturated fatty acids especially eicosapentaenoic acid (EPA) demonstrated anti-thrombus effect due to change in fatty acid composition of lipids. In the present study, adenosine 5'-diphosphoric acid (ADP)-induced platelet aggregation and inhibition of platelet aggregation by a prostaglandin Iz derivative were not influenced by the treatment of rats with sardine oil or cotton seed oil, unexpectedly. Further examination should be needed to clarify the anti-thrombus effect of fish oil. | |||||
言語 | en | |||||
書誌情報 |
ja : 水産大学校研究報告 en : Journal of National Fisheries University 巻 54, 号 2, p. 43-53, ページ数 11, 発行日 2006-03 |
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出版者 | ||||||
出版者 | 水産大学校 | |||||
言語 | ja | |||||
出版者 | ||||||
出版者 | National Fisheries University | |||||
言語 | en | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0370-9361 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00124678 | |||||
情報源 | ||||||
識別子タイプ | Local | |||||
関連識別子 | fishu_k_54_43 | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://agriknowledge.affrc.go.jp/RN/2010731277 | |||||
言語 | en | |||||
関連名称 | agriknowledge |