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マウス耳介浮腫に対する褐藻サガラメ由来の脂溶性成分による抑制効果
https://fra.repo.nii.ac.jp/records/2012106
https://fra.repo.nii.ac.jp/records/20121063f6b7aa4-744e-46f0-a0b3-34de9e8482fd
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
fishu_k_65_245.pdf (1.3 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||
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| 公開日 | 2024-10-11 | |||||||||||
| タイトル | ||||||||||||
| タイトル | マウス耳介浮腫に対する褐藻サガラメ由来の脂溶性成分による抑制効果 | |||||||||||
| 言語 | ja | |||||||||||
| タイトル | ||||||||||||
| タイトル | The suppressive effect of the lipophilic fraction of Eisenia arborea on ear swelling in mice | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | jpn | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Eisenia arborea; anti-inflammation; allergic reactions; lipophilic fraction | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
| 著者 |
杉浦, 義正
× 杉浦, 義正
WEKO
1243
× 臼井, 将勝× 宮田, 昌明 |
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | The anti-inflammatory effects of phlorotannins identified in the hydrophilic fraction of the brown alga, Eisenia arborea, were previously determined in vivo and in vitro. Here, we investigated the in vivo effect of the lipophilic fraction from this alga in mice. In ICR mice, ear swelling was induced by three sensitizers: arachidonic acid (AA), 12-O-tetradecanoylphorbol-13-acetate (TPA) and oxazolone (OXA). Swelling induced by AA or TPA was suppressed in a dose dependent manner after the said lipophilic fraction was applied to the mouse ears at a dose of 0.01, 0.1 and 1 mg/mouse, respectively. The suppression was similar to that by epigallocatechin gallate (EGCG), a typical natural inhibitor. On the other hand, the suppressive effect of the fraction at 1 mg/mouse on ear swelling induced by OXA was significantly lower than that of EGCG (ρ < 0.01). At a dose of 0.01 and 0.1 mg/mouse, no suppression by the fraction was observed. Therefore, lipophilic active components in the fraction may suppress immediate inflammatory reactions induced by AA or TP A, but not show suppressive effects on the delayed-type (type IV allergy) inflammatory reactions induced by OXA. | |||||||||||
| 言語 | en | |||||||||||
| 書誌情報 |
ja : 水産大学校研究報告 en : Journal of National Fisheries University 巻 65, 号 4, p. 245-250, ページ数 6, 発行日 2017-03 |
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| 出版者 | ||||||||||||
| 出版者 | 水産大学校 | |||||||||||
| 言語 | ja | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | National Fisheries University | |||||||||||
| 言語 | en | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 0370-9361 | |||||||||||
| 書誌レコードID | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AN00124678 | |||||||||||
| 情報源 | ||||||||||||
| 識別子タイプ | Local | |||||||||||
| 関連識別子 | fishu_k_65_245 | |||||||||||
| 関連サイト | ||||||||||||
| 識別子タイプ | URI | |||||||||||
| 関連識別子 | https://agriknowledge.affrc.go.jp/RN/2010922174 | |||||||||||
| 言語 | en | |||||||||||
| 関連名称 | agriknowledge | |||||||||||
